In the popular sitcom "Two and a Half Men," Jenny McCarthy played the love interest of Charlie Sheen's character. Shocking news hit when Sheen announced he was HIV positive in 2015, four years after leaving the show. McCarthy expressed bitterness and concern over his revelation, voicing her anxiety about scenes they had shared and possible exposure. Other actors like Lindsay Lohan and Jennifer Taylor showed support for Sheen despite his tumultuous exit from the show following inflammatory remarks about show creator Chuck Lorre. However, McCarthy called out Sheen's irresponsibility, saying he needs to be accountable for his actions. Sheen responded to these comments sarcastically, stating he tested positive for HIV after his departure from the show and slyly suggesting McCarthy should improve her maths skills, insinuating that she had nothing to worry about with regards to potential exposure.